Covid Vaccines for Kids Are Coming, but Not for Many Months
While high-risk adults are immunized against coronovirus for the Kovid-19 line, many parents want to know: When will my child get the vaccine?
Short answer: not before late summer.
Pfizer and Moderna Children aged 12 and older have been enrolled in clinical trials of their vaccines and the results are expected by summer. Depending on how vaccines perform in that age group, companies may test them in younger children. The Food and Drug Administration typically takes a few weeks to review data from a clinical trial and authorize a vaccine.
Three other companies, Johnson & Johnson, Novavax and AstraZeneca, also plan to test their vaccines in children, but they lag behind.
When researchers first test drugs or vaccines in adults, they typically move the brackets of age, watching for any changes in effective doses and unexpected side effects.
“In an early stage it would be very unusual for children to start going down,” Dr. Said Emily Erbelding, an infectious disease doctor at the National Institutes of Health, who oversees testing of Kovid-19 vaccines in special populations.
Some vaccines – those that protect against pneumococcal or meningococcal bacteria or rotaviruses, for example – were previously tested in children because they prevent pediatrics. But it was first tested for a coronovirus vaccine and authorized for adults because the risk of serious illness and death from Kovid-19 rises steadily with age, Paul Offit, a professor at the University of Pennsylvania and the FDA Are members of Vaccine Advisory Panel.
“We are trying to save lives, keep people out of the ICU, save them from dying,” Dr. Offit said. This means prioritizing vaccines for older people and for people with underlying conditions.
About a quarter of the population in the United States are under 21, but they account for less than 1 percent of Kovid-19 deaths. Still, approximately 2 percent of children receiving Kovid-19 require hospital care, and at least 227 children in the United States have died of the disease.
“It is an important disease in children, not necessarily when you compare it to adults,” Dr. Pediatrician and Vaccine Specialist at Mount Sinai Hospital in New York. Kristin Oliver said.
Herd immunity will also require children to be vaccinated for the United States – this long-promised goal, at which the epidemic stops as the virus goes out to infect people.
Scientists have estimated that 70 to 90 percent of the population is expected to be widely disseminated in the country, especially with more infectious variants, which may need to be vaccinated against coronovirus.
“Not all adults can get the vaccine because there is some reluctance, or perhaps even some weakened immune system that just doesn’t respond,” Dr. Erbelting said. “I think if we are going for herd immunity then we have to involve the children.”
He also said that it would be important to vaccinate children in racial and ethnic populations who are most affected by the epidemic.
Clinical trials of Pfizer and Modern in adults each involved approximately 50,000 participants. They had to grow so large to show a significant difference between the volunteers receiving the vaccine and the placebo. But because it is rare for children to become seriously ill with Kovid-19, such a trial design would not be possible in children, as it would require many more participants to show the effect.
Instead, companies will look to vaccinated children for signs of a strong immune response that will protect them from coronaviruses.
Pfizer-BioNTech Vaccine Was Authorized in December For someone 16 and older. The company has continued its trial to recruit young volunteers. 2,259 teenagers ages 12 to 15. Teenagers are roughly Twice as likely to be infected According to the Centers for Disease Control and Prevention with coronoviruses as young children.
Results of that test should be available by summer, Pfizer spokesperson Kina Gazvini said.
“A child under 12 years old will need a new study and possibly a revised formulation or dosing program,” Ms Gajwini said. He said the test was likely to begin at the end of the year, but the plan would be finalized when the company would have data on older children.
Modern’s vaccine, which was also authorized in December, is on a similar track for pediatric testing. In December, the company Started testing Teens are aged between 12 and 17, and they plan Enroll 3,000 volunteers in this age group. The company expects the results to be “around midyear 2021”, Modern spokesperson Colleen Hussey said.
Based on the results, Adhunik plans to assess the vaccine in children between the ages of 6 months and 11 years later this year.
Babies may have some Antibodies at birth From vaccinated or infected mothers, but that maternal protection is unlikely to occur until the first year of age. And with their relatively weak immune system, infants may be particularly susceptible to infection if community transmission is high.
The test will also assess the safety of the vaccine in children – and is expected to alleviate any parental fears. A third of adults in the United States have said they do not plan to immunize their children against coronaviruses, according to one Fresh voting Powered by Wellwell Health.
Dr. Ophitt said that given the low risk of Kovid-19 in children, some parents may doubt the urgency to vaccinate their children with brand-new jabs. “For this reason, the vaccine will have to be held to a very high level of safety,” he said.
More than 42 million people have been immunized so far in the United States, with few lasting side effects. And the FDA has established several systems to carefully monitor any serious reactions to the vaccine.
“They are really looking at the data very closely,” Dr. Oliver said. “As a pediatrician and a mother, I have really good faith that those systems work.”
Once a vaccine is available to children, schools can resume additional activities, including close contact, such as band practice, team games and singing. Dr. Oliver said that in the meantime, there is enough evidence that the schools could reopen with other precautions.
“I don’t think we need to presume to have a vaccine to open schools in the fall,” she said. “We should plan from now on to open a school.”
Dr. Oliver also urged parents to ensure that children are immune to other diseases. According to the CDC, non-flu orders for childhood through vaccines Vaccines for children program About 10.3 million doses are below all.
“Now is the time to really catch the missed dose of those vaccines,” she said. “Measles, HPV, Tetanus Booster, Pertussis Booster – it’s all really important.”